NEURA CUBE RESEARCH & INNOVATION LABS

Building Next-Generation Surgical Machines & Clinical AI

At Neura Cube, our engineering and clinical research teams are pioneering autonomous surgical robotics, augmented reality navigation, real-time 2D-to-3D anatomical reconstruction, and AI-guided precision neuro & spine surgery.

Peer-Reviewed Publications

Published Research Papers

Journal of Minimally Invasive Spine Surgery and Technique (JMISST) • Review Article • 2026; 11(2): 180-190

Authors: Wongthawat Liawrungrueang, Kang Taek Lim, Saidileep Viswanadha, Watcharaporn Cholamjiak, Peem Sarasombath, Chaiyapruk Pundee, Sung Tan Cho, Meng-Huang Wu, Didier Demesmin, Don Young Park

Published Online: October 30, 2026  |  DOI: 10.21182/jmisst.2026.03699

This study evaluates current trends, clinical applications, and limitations of augmented reality (AR) in endoscopic spine surgery (ESS). Conducted in accordance with PRISMA 2020 guidelines across PubMed/MEDLINE, Scopus, Web of Science, Embase, and Google Scholar (2019–2026), this systematic review synthesizes real-world clinical insights on head-mounted displays, real-time 3D anatomical navigation overlays, surgical ergonomics, radiation reduction, and trajectory precision in minimally invasive endoscopic spine procedures.

Keywords: Augmented reality; Endoscopic spine surgery; Minimally invasive spine surgery; Ergonomics; Visualization; Systematic review

Research Domains

Core Pillars of Our Surgical Innovation

Next-Generation Surgical Machines

Developing high-precision robotic surgical platforms with sub-millimeter kinematic control, haptic feedback, and intelligent trajectory execution for minimally invasive spine and cranial interventions.

Augmented Reality & 3D Intraoperative Vision

Real-time 2D-to-3D anatomical conversion, AR endoscopic navigation, and deep-learning segmentation of critical neural and vascular structures during live procedures.

Patient-Specific Digital Twins & VR

Biomechanical digital twin modeling and immersive VR surgical simulation that enable surgeons to rehearse complex cases, predict tissue deformation, and optimize surgical plans.

Collaborate on Surgical Robotics & Clinical AI Research

Interested in clinical trial partnerships or academic collaboration on our next-generation surgery machines and augmented reality spine navigation? Connect with the Neura Cube research team through our portal.

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